Our research interests, which primarily relate to metabolism and heart failure, include:

• Understanding the mechanisms of cardiac muscle damage during a heart attack and developing novel therapeutics to preserve the heart.
• Elucidating the molecular regulation of cardiac hypertrophy and the transition to heart failure.
• Investigating the confounding influence of risk factors (such as diabetes) on the development of heart disease.
• Uncovering the pathophysiology of fibroblasts/fibrosis in ventricular remodeling.

In all such endeavors, the laboratory group invokes a multidisciplinary approach to answer important questions in a variety of in vivo and in vitro models. My laboratory is also dedicated to providing a fertile environment for students and fellows to gain the necessary experience and guidance to become independent investigators.